We use cookies to improve your online experience. By continuing browsing this website, we assume you agree our use of cookies.

Aminolevulinic Acid HCL (5-ALA HCL) Powder

Item No.: 5-ALA HCL Powder
Product Name: Aminolevulinic Acid HCL
Other Name:  5-ALA HCL
CAS Number: 5451-09-2
Purity (HPLC): ≥98%
Appearance: White to off-white crystalline powder
Solubility: Water-soluble (>500 mg/mL); slightly soluble in methanol
Description

Product Description

Aminolevulinic Acid HCl (5-ALA HCl) is a naturally occurring amino acid derivative that serves as a precursor in heme biosynthesis. In cosmetic applications, this water-soluble active is metabolized to Protoporphyrin IX (PpIX), a photosensitizing compound that interacts with specific light therapies for skin rejuvenation and acne treatment.

Our Cosmetic Grade Aminolevulinic Acid HCl is produced via microbial fermentation and ion exchange purification, meeting ≥98% purity (HPLC). It appears as a white to off-white crystalline powder with excellent water solubility (>500 mg/mL).

 

Quick Details

Parameter                        

Specification

Product Name

Aminolevulinic Acid HCl

Other Name

5-ALA HCl

CAS Number

5451-09-2

Molecular Formula

C₅H₁₀ClNO₃

Molecular Weight

167.59 g/mol

Purity (HPLC)

≥98%

Appearance

White to off-white crystalline powder

Solubility

Water-soluble (>500 mg/mL); slightly soluble in methanol

Melting Point

151–157°C (decomposes)

Storage

Sealed, light-protected, cool and dry; 2–8°C recommended

Shelf Life

12–24 months

 

Key Characteristics

Fermentation-Derived — Produced through microbial fermentation using genetically engineered Corynebacterium glutamicum, ensuring consistent quality and high purity.

Water-Soluble Active — Excellent aqueous solubility makes it easy to incorporate into serums, toners, and gel-based formulations without special solubilizers.

Photosensitizing Precursor — In specific professional applications, 5-ALA is metabolized to PpIX, which accumulates intracellularly and interacts with specific light wavelengths.

Light-Sensitive — Requires protection from light during storage and formulation; finished products should use opaque packaging.

 

The Main Applications for Aminolevulinic Acid HCL (5-ALA HCL) Powder?

1) Professional Skincare (Light-Assisted Protocols)
In professional settings, 5-ALA is incorporated into formulations used in conjunction with specific light-based protocols for skin rejuvenation and acne management.

2) Anti-Aging & Skin Renewal Formulations
Patented formulations describe the use of 5-ALA in cosmetic compositions targeting skin appearance improvement, including skin texture and firmness.

3) Rinse-off Products
5-ALA HCl is suitable for rinse-off applications including cleansers, body washes, and hair care products at the regulated concentrations.

 

Why Choose Our Aminolevulinic Acid HCl?

 Fermentation-derived — consistent quality via microbial production

 ≥98% HPLC purity — verified potency for demanding formulations

 Water-soluble — easy incorporation into aqueous systems

 Full documentation — COA, MSDS, TDS available upon request

 

Request some sample or want to order the Aminolevulinic Acid HCL(5-ALA HCL) PowderContact DIELEGANCE BIOTECH technical sales team to ask more details for supporting your formulations. 

Review

1/3
X
t