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Astragalus Root Extract & Astragaloside IV: Comprehensive Guide to Standardized Botanical and High-Purity Saponin for Advanced Formulations

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Author : Samantha Song
Update time : 2026-09-01 15:05:08

Introduction

Astragalus membranaceus (Fisch.) Bunge, a perennial plant belonging to the Fabaceae family, has been used in traditional wellness practices for centuries. Astragaloside IV (CAS 84687-43-4) stands out as the most extensively studied tetracyclic triterpenoid saponin, recognized as a key quality indicator for Astragalus root extracts in pharmacopoeial standards. At Dielegance Biotech, we offer two complementary grades to meet diverse formulation needs: Astragalus Root Extract standardized to 5% Astragaloside IV and High-Purity Astragaloside IV 98%.

 

Understanding the Difference: Standardized Extract vs. High-Purity Monomer

Property

5% Standardized Extract

98% Astragaloside IV Monomer

Product Nature

Multi-component botanical extract

Purified single-compound saponin

Active Content

≥5.0% Astragaloside IV (HPLC)

≥98.0% Astragaloside IV (HPLC)

Appearance

Brown-yellow to light yellow powder

White to off-white fine powder

Contains

Astragaloside IV + polysaccharides, flavonoids, other saponins

Single purified compound

Solubility

Good water solubility

Soluble in DMSO, ethanol, methanol; practically insoluble in water

Melting Point

295–296°C (dec.)

Molecular Weight

784.98 g/mol

Storage

Cool, dry, light-protected

-10°C to -20°C; under inert gas; hygroscopic

Typical Application

Dietary supplements, functional foods

Premium supplements, advanced skincare, research-grade applications

Dosing Level

300–900 mg/day (extract)

50–200 mg/day (pure compound)


Applications for Astragalus Root Extract Astragaloside IV Powder

Dietary Supplements and Nutraceuticals

5% Standardized Extract is widely used in supplement formulations targeting:

  • Immune system support and vitality

  • Cardiovascular wellness

  • Healthy aging and cellular health

  • Stress adaptation support

98% Astragaloside IV is suitable for premium supplement formulations requiring:

  • Precise, low-dose active ingredient delivery

  • Research-grade purity for some products

  • Telomere-support formulations

Common Formats:

  • Capsules and tablets (300–900 mg extract or 50–200 mg pure compound)

  • Powder blends for functional beverages

  • Liquid tinctures and drops

  • Formulation with advanced delivery systems
     

Cosmetics and Personal Care

Both grades are increasingly incorporated into premium skincare formulations for anti-aging, skin firming, and barrier support applications.

Common Formats:

  • Anti-aging serums and creams

  • Firming lotions and treatments

  • Barrier-repair formulations

  • Advanced delivery systems (ethosomes, liposomes)
     

Research and Reference Standards

The 98% purity grade also serves as a research-grade material for analytical reference and biological studies.

 

Critical Process Guidelines:
Temperature: Sensitive to heat; avoid processing above 60°C
Storage: Must be stored frozen (-10°C to -20°C) under inert gas 
Moisture: Hygroscopic; protect from moisture during handling 
Light: Protect from strong light exposure
Aliquot: Divide into single-use portions to maintain stability

 

 

Why Choose Our Astragalus Root Extract Astragaloside IV Powder?

✅ Two complementary grades — 5% standardized extract and 98% high-purity monomer

✅ HPLC-verified potency — consistent batch-to-batch quality

✅ Full batch traceability — from cultivated roots to finished powder

✅ Comprehensive documentation — CoA, MSDS, TDS available

✅ Technical formulation support — assistance with stability and application


✅ Flexible supply options — quantities to meet your production needs

 

Request some sample or want to order, Contact DIELEGANCE BIOTECH technical sales team to ask more details for supporting your formulations.

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